Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract

Isaac John Umaru

doi:doi:10.11648/j.ab.20210903.11

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Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract

Isaac John Umaru

Published in Advances in Biochemistry (Volume 9, Issue 3)

Received: 11 May 2021 Accepted: 28 May 2021 Published: 18 August 2021

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Abstract

Introduction: Antibiotic resistance is a global problem that threat the public health. New patterns of antimicrobial resistance emerge daily which get through the international boundaries and easily spread. The aim of this study is to evaluate the activity of Euphorbia trigona rubra leaves crude extract on this drug resistance bacteria’s. Materials and methods: This study was carried out in natural product laboratory in collaboration with Microbiology Laboratory. Antimicrobial sensitivity patterns of the bacteria were done by using Kirby Bauer Disc Diffusion method. Antibiotics which were tested in congruent with the crude extract include Augmentin (10 μg), Amoxicillin (10 μg), Ampicillin (10 μg), Cefixime (30 μg), Ticarcillin (30 μg), Ceftazidime (30 μg), Azithromycin (15 μg), Gentamycin (10 mcg), Ciprofloxacin (10 μg), Trimethoprim-Sulfamethaxazole (10 μg), Doxycycline (30 μg), Chloramphenicol (30 μg), and Rifampicin (30 μg). Results: Euphorbia trigona rubra leaves crude extract has shown a significant activity of 21.33±0.55 mm when compared to the drug (4.63±0.71 mm, 7.33±0.55 mm, 4.00±0.06 mm, 4.58±0.21 mm, 7.11±1.00 mm, 5.97±0.87 mm, 4.63±0.71 mm, 7.33±0.55 mm, 5.00±0.06 mm, 5.58±0.21 mm, 5.97±0.87 mm, 4.63±0.71 mm, and 9.13±0.55 mm) at 500 µg/mL, respectively that the bacterium was resistance to, this shows that the crude extract from the leaves of this cactus plant has an effective activity for resistance bacteria and should be considered as an agent in the pharmaceutical industries.

Published in	Advances in Biochemistry (Volume 9, Issue 3)
DOI	10.11648/j.ab.20210903.11
Page(s)	39-43
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Antibiotic, Pseudomonas aeruginosa, Euphorbia trigona rubra, Leaves

References

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APA Style

Isaac John Umaru. (2021). Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract. Advances in Biochemistry, 9(3), 39-43. https://doi.org/10.11648/j.ab.20210903.11

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ACS Style

Isaac John Umaru. Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract. Adv. Biochem. 2021, 9(3), 39-43. doi: 10.11648/j.ab.20210903.11

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AMA Style

Isaac John Umaru. Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract. Adv Biochem. 2021;9(3):39-43. doi: 10.11648/j.ab.20210903.11

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@article{10.11648/j.ab.20210903.11,
  author = {Isaac John Umaru},
  title = {Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract},
  journal = {Advances in Biochemistry},
  volume = {9},
  number = {3},
  pages = {39-43},
  doi = {10.11648/j.ab.20210903.11},
  url = {https://doi.org/10.11648/j.ab.20210903.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20210903.11},
  abstract = {Introduction: Antibiotic resistance is a global problem that threat the public health. New patterns of antimicrobial resistance emerge daily which get through the international boundaries and easily spread. The aim of this study is to evaluate the activity of Euphorbia trigona rubra leaves crude extract on this drug resistance bacteria’s. Materials and methods: This study was carried out in natural product laboratory in collaboration with Microbiology Laboratory. Antimicrobial sensitivity patterns of the bacteria were done by using Kirby Bauer Disc Diffusion method. Antibiotics which were tested in congruent with the crude extract include Augmentin (10 μg), Amoxicillin (10 μg), Ampicillin (10 μg), Cefixime (30 μg), Ticarcillin (30 μg), Ceftazidime (30 μg), Azithromycin (15 μg), Gentamycin (10 mcg), Ciprofloxacin (10 μg), Trimethoprim-Sulfamethaxazole (10 μg), Doxycycline (30 μg), Chloramphenicol (30 μg), and Rifampicin (30 μg). Results: Euphorbia trigona rubra leaves crude extract has shown a significant activity of 21.33±0.55 mm when compared to the drug (4.63±0.71 mm, 7.33±0.55 mm, 4.00±0.06 mm, 4.58±0.21 mm, 7.11±1.00 mm, 5.97±0.87 mm, 4.63±0.71 mm, 7.33±0.55 mm, 5.00±0.06 mm, 5.58±0.21 mm, 5.97±0.87 mm, 4.63±0.71 mm, and 9.13±0.55 mm) at 500 µg/mL, respectively that the bacterium was resistance to, this shows that the crude extract from the leaves of this cactus plant has an effective activity for resistance bacteria and should be considered as an agent in the pharmaceutical industries.},
 year = {2021}
}

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TY  - JOUR
T1  - Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract
AU  - Isaac John Umaru
Y1  - 2021/08/18
PY  - 2021
N1  - https://doi.org/10.11648/j.ab.20210903.11
DO  - 10.11648/j.ab.20210903.11
T2  - Advances in Biochemistry
JF  - Advances in Biochemistry
JO  - Advances in Biochemistry
SP  - 39
EP  - 43
PB  - Science Publishing Group
SN  - 2329-0862
UR  - https://doi.org/10.11648/j.ab.20210903.11
AB  - Introduction: Antibiotic resistance is a global problem that threat the public health. New patterns of antimicrobial resistance emerge daily which get through the international boundaries and easily spread. The aim of this study is to evaluate the activity of Euphorbia trigona rubra leaves crude extract on this drug resistance bacteria’s. Materials and methods: This study was carried out in natural product laboratory in collaboration with Microbiology Laboratory. Antimicrobial sensitivity patterns of the bacteria were done by using Kirby Bauer Disc Diffusion method. Antibiotics which were tested in congruent with the crude extract include Augmentin (10 μg), Amoxicillin (10 μg), Ampicillin (10 μg), Cefixime (30 μg), Ticarcillin (30 μg), Ceftazidime (30 μg), Azithromycin (15 μg), Gentamycin (10 mcg), Ciprofloxacin (10 μg), Trimethoprim-Sulfamethaxazole (10 μg), Doxycycline (30 μg), Chloramphenicol (30 μg), and Rifampicin (30 μg). Results: Euphorbia trigona rubra leaves crude extract has shown a significant activity of 21.33±0.55 mm when compared to the drug (4.63±0.71 mm, 7.33±0.55 mm, 4.00±0.06 mm, 4.58±0.21 mm, 7.11±1.00 mm, 5.97±0.87 mm, 4.63±0.71 mm, 7.33±0.55 mm, 5.00±0.06 mm, 5.58±0.21 mm, 5.97±0.87 mm, 4.63±0.71 mm, and 9.13±0.55 mm) at 500 µg/mL, respectively that the bacterium was resistance to, this shows that the crude extract from the leaves of this cactus plant has an effective activity for resistance bacteria and should be considered as an agent in the pharmaceutical industries.
VL  - 9
IS  - 3
ER  -

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Author Information

Isaac John Umaru

Department of Biochemistry, Federal University, Wukari, Nigeria

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Isaac John Umaru. (2021). Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract. Advances in Biochemistry, 9(3), 39-43. https://doi.org/10.11648/j.ab.20210903.11

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ACS Style

Isaac John Umaru. Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract. Adv. Biochem. 2021, 9(3), 39-43. doi: 10.11648/j.ab.20210903.11

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AMA Style

Isaac John Umaru. Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract. Adv Biochem. 2021;9(3):39-43. doi: 10.11648/j.ab.20210903.11

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@article{10.11648/j.ab.20210903.11,
  author = {Isaac John Umaru},
  title = {Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract},
  journal = {Advances in Biochemistry},
  volume = {9},
  number = {3},
  pages = {39-43},
  doi = {10.11648/j.ab.20210903.11},
  url = {https://doi.org/10.11648/j.ab.20210903.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20210903.11},
  abstract = {Introduction: Antibiotic resistance is a global problem that threat the public health. New patterns of antimicrobial resistance emerge daily which get through the international boundaries and easily spread. The aim of this study is to evaluate the activity of Euphorbia trigona rubra leaves crude extract on this drug resistance bacteria’s. Materials and methods: This study was carried out in natural product laboratory in collaboration with Microbiology Laboratory. Antimicrobial sensitivity patterns of the bacteria were done by using Kirby Bauer Disc Diffusion method. Antibiotics which were tested in congruent with the crude extract include Augmentin (10 μg), Amoxicillin (10 μg), Ampicillin (10 μg), Cefixime (30 μg), Ticarcillin (30 μg), Ceftazidime (30 μg), Azithromycin (15 μg), Gentamycin (10 mcg), Ciprofloxacin (10 μg), Trimethoprim-Sulfamethaxazole (10 μg), Doxycycline (30 μg), Chloramphenicol (30 μg), and Rifampicin (30 μg). Results: Euphorbia trigona rubra leaves crude extract has shown a significant activity of 21.33±0.55 mm when compared to the drug (4.63±0.71 mm, 7.33±0.55 mm, 4.00±0.06 mm, 4.58±0.21 mm, 7.11±1.00 mm, 5.97±0.87 mm, 4.63±0.71 mm, 7.33±0.55 mm, 5.00±0.06 mm, 5.58±0.21 mm, 5.97±0.87 mm, 4.63±0.71 mm, and 9.13±0.55 mm) at 500 µg/mL, respectively that the bacterium was resistance to, this shows that the crude extract from the leaves of this cactus plant has an effective activity for resistance bacteria and should be considered as an agent in the pharmaceutical industries.},
 year = {2021}
}

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TY  - JOUR
T1  - Antibiotic Resistance of “Pseudomonas aeruginosa” and the Effect of Euphorbia trigona rubra Leaves Crude Extract
AU  - Isaac John Umaru
Y1  - 2021/08/18
PY  - 2021
N1  - https://doi.org/10.11648/j.ab.20210903.11
DO  - 10.11648/j.ab.20210903.11
T2  - Advances in Biochemistry
JF  - Advances in Biochemistry
JO  - Advances in Biochemistry
SP  - 39
EP  - 43
PB  - Science Publishing Group
SN  - 2329-0862
UR  - https://doi.org/10.11648/j.ab.20210903.11
AB  - Introduction: Antibiotic resistance is a global problem that threat the public health. New patterns of antimicrobial resistance emerge daily which get through the international boundaries and easily spread. The aim of this study is to evaluate the activity of Euphorbia trigona rubra leaves crude extract on this drug resistance bacteria’s. Materials and methods: This study was carried out in natural product laboratory in collaboration with Microbiology Laboratory. Antimicrobial sensitivity patterns of the bacteria were done by using Kirby Bauer Disc Diffusion method. Antibiotics which were tested in congruent with the crude extract include Augmentin (10 μg), Amoxicillin (10 μg), Ampicillin (10 μg), Cefixime (30 μg), Ticarcillin (30 μg), Ceftazidime (30 μg), Azithromycin (15 μg), Gentamycin (10 mcg), Ciprofloxacin (10 μg), Trimethoprim-Sulfamethaxazole (10 μg), Doxycycline (30 μg), Chloramphenicol (30 μg), and Rifampicin (30 μg). Results: Euphorbia trigona rubra leaves crude extract has shown a significant activity of 21.33±0.55 mm when compared to the drug (4.63±0.71 mm, 7.33±0.55 mm, 4.00±0.06 mm, 4.58±0.21 mm, 7.11±1.00 mm, 5.97±0.87 mm, 4.63±0.71 mm, 7.33±0.55 mm, 5.00±0.06 mm, 5.58±0.21 mm, 5.97±0.87 mm, 4.63±0.71 mm, and 9.13±0.55 mm) at 500 µg/mL, respectively that the bacterium was resistance to, this shows that the crude extract from the leaves of this cactus plant has an effective activity for resistance bacteria and should be considered as an agent in the pharmaceutical industries.
VL  - 9
IS  - 3
ER  -

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