Volume 6, Issue 4, August 2018, Page: 32-38
Phytochemical Screening, Chemical Composition and Antioxidant Activity of Leaves and Bark Extracts from Khaya senegalensis
Marvit Osman Widdat Allah, Department of Pharmacology, Faculty of Pharmacy, University of Medical Sciences and Technology, Khartoum, Sudan
Ayat Ahmed Alrasheid, Department of Pharmacognosy, Faculty of Pharmacy, University of Medical Sciences and Technology, Khartoum, Sudan
Altayeb Suliman Elamin, Department of Pharmaceutics, Faculty of Pharmacy, Omdurman Islamic University, Khartoum, Sudan
Received: Sep. 5, 2018;       Accepted: Sep. 30, 2018;       Published: Nov. 1, 2018
DOI: 10.11648/j.ab.20180604.12      View  237      Downloads  19
Khaya senegalensis belonging to family Meliaceae. This plant has been used as traditional medicine for several disease such as pain, inflammation, malaria, anemia, diabetic and gastrointestinal diseases. The objective of this study to carry out phytochemical screening, determination of chemical composition and determine antioxidant activity of plant extracts. Many of secondary metabolites were investigated in leaves extract include alkaloids, flavonoids, sterols and saponins while the bark extract includes sterols, triterpines, tannins and saponins. The antioxidant potential of ethanol extract of leaves and bark was determined on the basis of their scavenging activity of the stable 1, 1-diphenyl-2-picryl hydrazyl (DPPH) free radical. Antioxidant activity of leaves extract was higher than bark with (42.69%) and (36.36%) respectively. The quantitative analysis of chemical composition was determined by Gas Chromatography–Mass Spectrometry (GC-MS). A number of bioactive compounds were present in the leaves and bark of K.senegalensis. The highest compound in both extracts represented the reducing sugar 4-O-Methyl mannose (66.47 and 14.73%) in bark and leaves respectively. Fatty acids and phenols were presented in high percentage in both extract include; n-Hexadecanoic acid, 9,12,15-Octadecatrienoic acid, Oleic Acid and Catechol.
Khaya senegalensis, Leaves, Bark, Phytochemical Screening, GC-MS Analysis, Antioxidant Activity
To cite this article
Marvit Osman Widdat Allah, Ayat Ahmed Alrasheid, Altayeb Suliman Elamin, Phytochemical Screening, Chemical Composition and Antioxidant Activity of Leaves and Bark Extracts from Khaya senegalensis, Advances in Biochemistry. Vol. 6, No. 4, 2018, pp. 32-38. doi: 10.11648/j.ab.20180604.12
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