Serum Electrolytes Profile During Accidental Acute Poisoning in Children at Charles De Gaulle Pediatric University Hospital of Ouagadougou

Fabienne Marie Soudre; Raoul Karfo; Alice Kiba; Arnaud Kouraogo; Rachid Sougue; Elie Kabre; Jean Sakande

doi:doi:10.11648/j.ab.20231102.11

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Serum Electrolytes Profile During Accidental Acute Poisoning in Children at Charles De Gaulle Pediatric University Hospital of Ouagadougou

Fabienne Marie Soudre, Raoul Karfo, Alice Kiba, Arnaud Kouraogo, Rachid Sougue, Elie Kabre, Jean Sakande

Published in Advances in Biochemistry (Volume 11, Issue 2)

Received: 10 May 2023 Accepted: 13 June 2023 Published: 27 June 2023

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Abstract

Accidental acute poisoning (AAP) in children is a significant public health problem worldwide. Their adequate management requires relevant biological elements. The objective of this study was to evaluate ionic disturbances during acute poisoning in children aged from 0 to 15 years admitted to the Charles De Gaulle Pediatric University Hospital (CHUP-CDG) of Ouagadougou, Burkina Faso. A retrospective descriptive and analytical study was therefore conducted over a period of 3 years at CHUP-CDG. It was performed in the pediatric, intensive care and laboratory departments of the CHUP-CDG, and involved children aged from 0 to 15 years with complete clinical records. A total of 193 patients were included, with a mean age of 18.82±24.85 months and M/F sex ratio of 1.38. The hospital incidence of AAP was 2.43% and the mortality rate 16.06%. Phytomedicinal intoxications were the most common (39.38%), followed by caustic products (19.69%). On admission, serum electrolytes showed hypobicarbonatemia (64.23%), hyperchloremia (55.24%), hyponatremia (33.78%), hypoproteinemia (21.47%) and hyperkalemia (12.16%). At control, hypobicarbonatemia (28.57%), hyperchloremia (75%), hypoproteinemia (28.57%), hyperkalemia (12.50%) and here hypernatremia (25%) were found. The deceased patients had significantly lower natremia (p=0.0442), chloremia (p=0.0007) and proteinemia (p=0.0004) than the other patients in the study. The high death rate was related to herbal medicines and caustic intoxications. Many hydroelectric disorders were found in the study. These disorders could be explain par digestive losses. Indeed, the main clinical signs found in the study were vomiting and diarrhea in children. In addition, acute renal failure in patients could also explain these ionic disturbances. AAP are at the root of multiple ionic disorders, which may be responsible for life-threatening complications in patients.

Published in	Advances in Biochemistry (Volume 11, Issue 2)
DOI	10.11648/j.ab.20231102.11
Page(s)	15-21
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Electrolytes, Sodium, Bicarbonates, Accidental Acute Poisoning, Child, CHUP-CDG, Burkina Faso

References

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APA Style

Fabienne Marie Soudre, Raoul Karfo, Alice Kiba, Arnaud Kouraogo, Rachid Sougue, et al. (2023). Serum Electrolytes Profile During Accidental Acute Poisoning in Children at Charles De Gaulle Pediatric University Hospital of Ouagadougou. Advances in Biochemistry, 11(2), 15-21. https://doi.org/10.11648/j.ab.20231102.11

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ACS Style

Fabienne Marie Soudre; Raoul Karfo; Alice Kiba; Arnaud Kouraogo; Rachid Sougue, et al. Serum Electrolytes Profile During Accidental Acute Poisoning in Children at Charles De Gaulle Pediatric University Hospital of Ouagadougou. Adv. Biochem. 2023, 11(2), 15-21. doi: 10.11648/j.ab.20231102.11

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AMA Style

Fabienne Marie Soudre, Raoul Karfo, Alice Kiba, Arnaud Kouraogo, Rachid Sougue, et al. Serum Electrolytes Profile During Accidental Acute Poisoning in Children at Charles De Gaulle Pediatric University Hospital of Ouagadougou. Adv Biochem. 2023;11(2):15-21. doi: 10.11648/j.ab.20231102.11

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@article{10.11648/j.ab.20231102.11,
  author = {Fabienne Marie Soudre and Raoul Karfo and Alice Kiba and Arnaud Kouraogo and Rachid Sougue and Elie Kabre and Jean Sakande},
  title = {Serum Electrolytes Profile During Accidental Acute Poisoning in Children at Charles De Gaulle Pediatric University Hospital of Ouagadougou},
  journal = {Advances in Biochemistry},
  volume = {11},
  number = {2},
  pages = {15-21},
  doi = {10.11648/j.ab.20231102.11},
  url = {https://doi.org/10.11648/j.ab.20231102.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20231102.11},
  abstract = {Accidental acute poisoning (AAP) in children is a significant public health problem worldwide. Their adequate management requires relevant biological elements. The objective of this study was to evaluate ionic disturbances during acute poisoning in children aged from 0 to 15 years admitted to the Charles De Gaulle Pediatric University Hospital (CHUP-CDG) of Ouagadougou, Burkina Faso. A retrospective descriptive and analytical study was therefore conducted over a period of 3 years at CHUP-CDG. It was performed in the pediatric, intensive care and laboratory departments of the CHUP-CDG, and involved children aged from 0 to 15 years with complete clinical records. A total of 193 patients were included, with a mean age of 18.82±24.85 months and M/F sex ratio of 1.38. The hospital incidence of AAP was 2.43% and the mortality rate 16.06%. Phytomedicinal intoxications were the most common (39.38%), followed by caustic products (19.69%). On admission, serum electrolytes showed hypobicarbonatemia (64.23%), hyperchloremia (55.24%), hyponatremia (33.78%), hypoproteinemia (21.47%) and hyperkalemia (12.16%). At control, hypobicarbonatemia (28.57%), hyperchloremia (75%), hypoproteinemia (28.57%), hyperkalemia (12.50%) and here hypernatremia (25%) were found. The deceased patients had significantly lower natremia (p=0.0442), chloremia (p=0.0007) and proteinemia (p=0.0004) than the other patients in the study. The high death rate was related to herbal medicines and caustic intoxications. Many hydroelectric disorders were found in the study. These disorders could be explain par digestive losses. Indeed, the main clinical signs found in the study were vomiting and diarrhea in children. In addition, acute renal failure in patients could also explain these ionic disturbances. AAP are at the root of multiple ionic disorders, which may be responsible for life-threatening complications in patients.},
 year = {2023}
}

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TY - JOUR
T1 - Serum Electrolytes Profile During Accidental Acute Poisoning in Children at Charles De Gaulle Pediatric University Hospital of Ouagadougou
AU - Fabienne Marie Soudre
AU - Raoul Karfo
AU - Alice Kiba
AU - Arnaud Kouraogo
AU - Rachid Sougue
AU - Elie Kabre
AU - Jean Sakande
Y1 - 2023/06/27
PY - 2023
N1 - https://doi.org/10.11648/j.ab.20231102.11
DO - 10.11648/j.ab.20231102.11
T2 - Advances in Biochemistry
JF - Advances in Biochemistry
JO - Advances in Biochemistry
SP - 15
EP - 21
PB - Science Publishing Group
SN - 2329-0862
UR - https://doi.org/10.11648/j.ab.20231102.11
AB - Accidental acute poisoning (AAP) in children is a significant public health problem worldwide. Their adequate management requires relevant biological elements. The objective of this study was to evaluate ionic disturbances during acute poisoning in children aged from 0 to 15 years admitted to the Charles De Gaulle Pediatric University Hospital (CHUP-CDG) of Ouagadougou, Burkina Faso. A retrospective descriptive and analytical study was therefore conducted over a period of 3 years at CHUP-CDG. It was performed in the pediatric, intensive care and laboratory departments of the CHUP-CDG, and involved children aged from 0 to 15 years with complete clinical records. A total of 193 patients were included, with a mean age of 18.82±24.85 months and M/F sex ratio of 1.38. The hospital incidence of AAP was 2.43% and the mortality rate 16.06%. Phytomedicinal intoxications were the most common (39.38%), followed by caustic products (19.69%). On admission, serum electrolytes showed hypobicarbonatemia (64.23%), hyperchloremia (55.24%), hyponatremia (33.78%), hypoproteinemia (21.47%) and hyperkalemia (12.16%). At control, hypobicarbonatemia (28.57%), hyperchloremia (75%), hypoproteinemia (28.57%), hyperkalemia (12.50%) and here hypernatremia (25%) were found. The deceased patients had significantly lower natremia (p=0.0442), chloremia (p=0.0007) and proteinemia (p=0.0004) than the other patients in the study. The high death rate was related to herbal medicines and caustic intoxications. Many hydroelectric disorders were found in the study. These disorders could be explain par digestive losses. Indeed, the main clinical signs found in the study were vomiting and diarrhea in children. In addition, acute renal failure in patients could also explain these ionic disturbances. AAP are at the root of multiple ionic disorders, which may be responsible for life-threatening complications in patients.
VL - 11
IS - 2
ER -

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Author Information

Fabienne Marie Soudre

Training and Research Unit in Health Sciences, Joseph Ki-Zerbo University, Ouagadougou, Burkina Faso
Raoul Karfo

Training and Research Unit in Health Sciences, Joseph Ki-Zerbo University, Ouagadougou, Burkina Faso
Alice Kiba

Training and Research Unit in Health Sciences, Joseph Ki-Zerbo University, Ouagadougou, Burkina Faso
Arnaud Kouraogo

Institute of Health Sciences, Nazi Boni University, Bobo-Dioulasso, Burkina Faso
Rachid Sougue

Training and Research Unit in Health Sciences, Joseph Ki-Zerbo University, Ouagadougou, Burkina Faso
Elie Kabre

Training and Research Unit in Health Sciences, Joseph Ki-Zerbo University, Ouagadougou, Burkina Faso
Jean Sakande

Training and Research Unit in Health Sciences, Joseph Ki-Zerbo University, Ouagadougou, Burkina Faso

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APA Style

Fabienne Marie Soudre, Raoul Karfo, Alice Kiba, Arnaud Kouraogo, Rachid Sougue, et al. (2023). Serum Electrolytes Profile During Accidental Acute Poisoning in Children at Charles De Gaulle Pediatric University Hospital of Ouagadougou. Advances in Biochemistry, 11(2), 15-21. https://doi.org/10.11648/j.ab.20231102.11

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ACS Style

Fabienne Marie Soudre; Raoul Karfo; Alice Kiba; Arnaud Kouraogo; Rachid Sougue, et al. Serum Electrolytes Profile During Accidental Acute Poisoning in Children at Charles De Gaulle Pediatric University Hospital of Ouagadougou. Adv. Biochem. 2023, 11(2), 15-21. doi: 10.11648/j.ab.20231102.11

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AMA Style

Fabienne Marie Soudre, Raoul Karfo, Alice Kiba, Arnaud Kouraogo, Rachid Sougue, et al. Serum Electrolytes Profile During Accidental Acute Poisoning in Children at Charles De Gaulle Pediatric University Hospital of Ouagadougou. Adv Biochem. 2023;11(2):15-21. doi: 10.11648/j.ab.20231102.11

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@article{10.11648/j.ab.20231102.11,
  author = {Fabienne Marie Soudre and Raoul Karfo and Alice Kiba and Arnaud Kouraogo and Rachid Sougue and Elie Kabre and Jean Sakande},
  title = {Serum Electrolytes Profile During Accidental Acute Poisoning in Children at Charles De Gaulle Pediatric University Hospital of Ouagadougou},
  journal = {Advances in Biochemistry},
  volume = {11},
  number = {2},
  pages = {15-21},
  doi = {10.11648/j.ab.20231102.11},
  url = {https://doi.org/10.11648/j.ab.20231102.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20231102.11},
  abstract = {Accidental acute poisoning (AAP) in children is a significant public health problem worldwide. Their adequate management requires relevant biological elements. The objective of this study was to evaluate ionic disturbances during acute poisoning in children aged from 0 to 15 years admitted to the Charles De Gaulle Pediatric University Hospital (CHUP-CDG) of Ouagadougou, Burkina Faso. A retrospective descriptive and analytical study was therefore conducted over a period of 3 years at CHUP-CDG. It was performed in the pediatric, intensive care and laboratory departments of the CHUP-CDG, and involved children aged from 0 to 15 years with complete clinical records. A total of 193 patients were included, with a mean age of 18.82±24.85 months and M/F sex ratio of 1.38. The hospital incidence of AAP was 2.43% and the mortality rate 16.06%. Phytomedicinal intoxications were the most common (39.38%), followed by caustic products (19.69%). On admission, serum electrolytes showed hypobicarbonatemia (64.23%), hyperchloremia (55.24%), hyponatremia (33.78%), hypoproteinemia (21.47%) and hyperkalemia (12.16%). At control, hypobicarbonatemia (28.57%), hyperchloremia (75%), hypoproteinemia (28.57%), hyperkalemia (12.50%) and here hypernatremia (25%) were found. The deceased patients had significantly lower natremia (p=0.0442), chloremia (p=0.0007) and proteinemia (p=0.0004) than the other patients in the study. The high death rate was related to herbal medicines and caustic intoxications. Many hydroelectric disorders were found in the study. These disorders could be explain par digestive losses. Indeed, the main clinical signs found in the study were vomiting and diarrhea in children. In addition, acute renal failure in patients could also explain these ionic disturbances. AAP are at the root of multiple ionic disorders, which may be responsible for life-threatening complications in patients.},
 year = {2023}
}

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